Biomarker analysis

FISH

Fluorescence in situ hybridization (FISH) is a molecular diagnostic technique utilizing fluorescently labeled DNA probes to detect gene or chromosome rearrangements, translocation, breakapart, amplification and deletion. FISH is used to monitor the effects of target therapy. Methods for Her2,  EGFR, c-met, TopoIIa, ALK-EML4, etc.